- Metabolic Syndrome in Patients with Migraine and Primary Headache Disorders: A Headache Clinic-Based Study
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Seung-Hee Na, Hyun Ah Choi, Hyun Jo Lee, Jeong-Wook Park, Joong-Seok Kim
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Published online December 31, 2014
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- 특발두개내압상승 환자에서 요추천자 후 발생한 두개내압저하두통
- 증례 : 말초 혈액의 호산구 증가 없이 발생한 호산구성 뇌막염
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Dong-Geun Lee, Joong-Seok Kim, In-Uk Song, Jeong-Wook Park, Kwang-Soo Lee
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Korean J Headache. 2006;7(2):112-114. Published online December 31, 2006
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- Eosinophilc meningitis is a rare clinical entity that can be useful in narrowing the differential diagnosis of central nervous system. The causes of eosinophilic meningitis are diverse: parasite infection, fungal infection, idiopathic hypereosinophilic syndrome, and Hodgkin's disease. But the most common cause of eosinophilic meningitis is invasion of the central nervous system by helminthic parasites, particularly Angiostrongylus cantonensis. And the most cases have occurred in Southeast Asia and throughout the Pacific basin, which are endemic areas. We report a patient with primary eosino- philic meningitis without eosinophilia.
- 증례 : 비행에 의해 유발되는 두통
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Young-Do Kim, In-Uk Song, Jeong-Wook Park, Joong-Seok Kim, Jae-Young An, Yeong-In Kim, Kwang-Soo Lee
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Korean J Headache. 2006;7(2):100-102. Published online December 31, 2006
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- A 46-year old man was admitted to neurology department because of severe headache associated only with airplane travel. When the plane started descending, a severe jabbing pain suddenly developed in the occipital area. The pain remained severe for 15 to 20 minutes until the plane landed. After the plane had landed, the pain alleviated spon- taneously and recovered completely after about 45 minutes. The brain computer tomography revealed chronic bilateral maxillary and right frontal sinusitis.
- 해면정맥동 이상이 선행하고 조직검사에서 확진된 톨로자헌트 증후군 1예
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Seon-Young Ryu, Sang-Bong Lee, Yeong-In Kim, Kwang-Soo Lee, Jeong-wook Park, Hye-Kyung Lee
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Korean J Headache. 2004;5(2):153-157. Published online December 31, 2004
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- Tolosa-Hunt syndrome(THS) is a painful ophthalmoplegia caused by an idiopathic granulomatous in- flammation of the superior orbital fissure or cavernous sinus of unknown etiology. A 72-year-old woman developed right-sided ophthalmoplegia with the pupillary dilatation and ptosis, and hypesthesia in the territory of the ophthalmic division of the right trigerminal nerve in May 2003. The MRI showed enlar- gement of right cavernous sinus by an enhancing soft tissue mass extending to the sellar region. Prior to this presentation, in August 2002, MRI done at another institusion already revealed the same soft tissue mass in the right cavernous sinus. The patient underwent a transsphenoidal biopsy which revealed chronic granulomatous inflammation with necrosis. The patient was treated with steroids, followed by the resolution of the neurologic symptoms. We report this case of biopsy-proven THS in which radiologic abnormality preceded clinical presentation by at least 10 months. Korean Journal of Headache 5(2):153-157, 2004
- Adult-Onset versus Pediatric-Onset Episodic Cluster Headaches: Results from the Korean Cluster Headache Registry
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Pil-Wook Chung, Byung-Su Kim, Jeong-Wook Park, Jong-Hee Sohn, Mi Ji Lee, Byung-Kun Kim, Min Kyung Chu, Tae-Jin Song, Soo-Kyoung Kim, Heui-Soo Moon, Kyungmi Oh, Soo-Jin Cho
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Received September 30, 2025 Accepted November 7, 2025 Published online December 10, 2025
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DOI: https://doi.org/10.62087/hpr.2025.0021
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Abstract
- Purpose: This study aimed to compare clinical characteristics between pediatric-onset and adult-onset cluster headache (CH) using data from the Korean Cluster Headache Registry, a nationwide, prospective, multicenter registry.
Methods
This cross-sectional observational study analyzed data collected over a 4-year period from a prospective multicenter registry. A total of 337 patients aged ≥19 years with episodic CH were included. Participants were classified as having pediatric-onset CH (onset≤18 years) or adult-onset CH (onset>18 years). Demographic and clinical features, smoking status, and psychiatric comorbidities were compared between groups.
Results
Pediatric-onset CH was reported in 24.6% of patients (n=83). The diagnostic delay was significantly longer in the pediatric-onset group compared with the adult-onset group (10.1 years vs. 6.2 years, p<0.001). Patients with pediatric-onset CH experienced more severe headache attacks (numerical rating scale 9.2 vs. 8.9, p=0.025), although attack duration, frequency, and other clinical features were similar between groups. Smoking exposure was lower in the pediatric-onset group, suggesting potential differences in environmental risk factors. No significant differences were observed in psychiatric comorbidity or headache-related disability.
Conclusion
Pediatric-onset CH is relatively common and shares most clinical features with adult-onset CH, apart from greater attack severity and lower smoking exposure. The longer diagnostic delay in pediatric-onset cases highlights the need for improved awareness and earlier recognition. Further research is warranted to elucidate the underlying pathophysiological mechanisms and long-term outcomes in pediatric-onset CH.
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