- CADASIL with Exon 6 Mutation Characterized as Migraine Without Aura and Later Onset
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Ga-Heon Jin, Gyeong-Seon Kim, Su-Ji Ban, Jun-Beom Lee
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Published online June 30, 2018
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 Abstract
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- 무조짐 편두통, 늦은 발병 연령이 특징인 엑손6번 유전자변이 CADASIL 환자
- 비출혈을 동반한 편두통 2례
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Jun-Beom Lee, Kwang-Hoon Kim, Ki-Hun Baek
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Korean J Headache. 2011;12(1):74-76. Published online June 30, 2011
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Abstract
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- We report two cases of migraine accompanying epistaxis. These attacks of epistaxis are not explained by reasons other than migraine attack. A 49-year-old woman had migraine with epistaxis for 6 years. She had nasal plastic surgery 15 years ago but rhinoscopy revealed no focal bleeding focus on Kisselbach plexus. Blood tests including platelet count and coagulation factors were normal. We prescribed her daily dose of acetaminophen 975mg along with dichloral- phenazone 300mg and isometheptene mucate 195mg. The incidence and severity of migraine reduced and epistaxis did not relapse. A 19-year-old woman had migraine attack once every one or two days for one month and experienced accompanying epistaxis one third of the frequency of headache attacks. Brain computed tomography, rhinoscopy, platelet count and coagulation factor tests were normal. Epistaxis following migraine attacks did not relapse after daily dose of acetaminophen 1,875mg. These cases suggest that migraine with epistaxis shares same pathophysiology.
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KHS
