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Volume 3(2); December 2002
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외상 후 두통
Yong-Jin Cho
Korean J Headache. 2002;3(2):83-92.   Published online December 31, 2002
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AbstractAbstract PDF
Post-traumatic headache is a new headache that follows a blunt or open injury to the head or brain. But there has been controversies surrounding the diagnosis of post-traumatic headache. The pathophysio- logy is not well known, either. On the other hand, the revision of IHS(International Headache Society) classification of headache will be scheduled on 2003. So it is helpful to review the clinical features, pathophysiology, treatment, and to preview the proposal for new diagnostic criterior of post-traumatic headache. Korean Journal of Headache 3(2):83-92, 2002
한국 대학생의 스포츠-연관성 두통의 유병률
Man-Wook Seo, Sun Young Oh
Korean J Headache. 2002;3(2):93-98.   Published online December 31, 2002
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AbstractAbstract PDF
Background
Previous studies suggested sports as a potent trigger of headaches. Compared with other headache syndromes, sports-related headaches(SRH) have attracted little academic interest. Therefore the precise epidemiology and characteristics of SRH remain uncertain. Methods: To investigate the characteristic features of SRH, we used a self-designed questionnaire, which was completed by 500 students of Jeonbuk National University in Korea. The subdivision of SRH was done based on clinical patterns. Results: Mean age of male-student respondents was 23.5±2.5 year old and that of female-student res- pondents was 21.6±1.5 year old. The prevalence of SRH among university students was 29.6%(148 of 500). The prevalence of SRH in male-students was slightly higher than that of female-students(30.3%, and 29.2%, respectively). The most common subtype of SRH, effort/ exertion headache, was slightly more prevalent in female students than in male students(94.4% and 92.2%, respectively). However, the prevalence of effort/exertion migraine in male students was slightly higher than that in female students (5.2% and 4.3%, respectively). Meanwhile, post-traumatic headache was found only in one male-student. A variety of sports and exercise were described as initiating SRH, sprinting being the most common. Whereas basketball and football predominantly initiated headache in male-students, sprinting and long distance running frequently caused headache in female-students. Precipitating factors were varied, the most common being cardiopulmonary overloading which accounted for 113(76%) of the SRH cases. Other precipitating factors were trauma, dehydration, heat, high altitude, hypoglycemia, and tiredness. Conclusions: This study demonstrated that sports- and exercise-related headaches are a common pro- blem among university students. Our results might be helpful to understand the characteristics of SRH and provide some basic information for future studies. Korean Journal of Headache 3(2):93-98, 2002
특발성 자두통의 임상 양상
Byung-Kun Kim, Hee-Joon Bae, Ja-Seong Koo, Oh-Hyun Kwon
Korean J Headache. 2002;3(2):99-104.   Published online December 31, 2002
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AbstractAbstract PDF
Background
Although idiopathic stabbing headache(ISH) seems to be very common primary head- ache with unique clinical features, previous descriptions about ISH were rather confusing. The classi- fication of the International Headache Society emphasized pain location confined to the distribution of the first division of the trigeminal nerve. Other terms describing ISH, such as ice-pick like pain, jab and jolts syndrome, sharp short lived head pain syndrome and ophthalmodynia, had some different clinical features each other. ISH also have been described in conjunction with migraine or cluster headache. However, in clinical practice, ISH occurs more frequently in extra-trigeminal region and is usually not associated with other primary headache syndromes. Methods: From Feb 2001 to August 2001, 1126 consecutive series of patients suffering from headache were examined in our neurology out-patients clinics. Among the patients, 50 patients presented stabbing headache with chief complaints. This sample consisted 21 males and 29 females aged from 12 to 79 years. Inclusion criteria were: (a) manifesting recurrent stabs on the head as a chief complaint, (b) wit- hout other organic causes. Results: The pain was more frequently localized extratrigeminal area(parietal, retroauricular or occipital) (60%), less frequently in the trigeminal area(20%), or both(20%). The orbital region was never affected. Regarding other coexisting forms of headache, only 20% suffered from other types of head- ache(migraine 6%, tension type headache 14%). No body had the associated autonomic features. In most patients(64%), the paroxysms lasted only 1~2s. The maximal frequency of attacks was variable, ranging from several tens to hundreds for one day. ISH was lasted from 1 to 36 days(mean 9.2±6.7 days). Conclusions: Our results show that the clinical features of ISH are somewhat different from previous studies by its location and its lack of association with migraine or cluster. All had benign course. Korean Journal of Headache 3(2):99-104, 2002
편두통 환자에서 이중 자극 순목 반사
Jae-Myun Chung, Kyung-Seok Park
Korean J Headache. 2002;3(2):105-109.   Published online December 31, 2002
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AbstractAbstract PDF
Background
Background: Trigeminovascular system is widely accepted hypothesis as an explanation for migraine pathogenesis. And the trigeminal nucleus in this system is believed to do a pivotal role. Recovery characteristics of R2 response to paired stimulations in blink reflex study is a practical and useful investigating tool for afferent trigeminal pathway as well as efferent facial nerve. Methods: We studied whether any difference in R2 recovery after paired stimulations is present between 9 patients of migraine without aura(MOA) and 9 migraine with aura(MWA) patients. Results: There was a difference in R2 recovery characteristics to paired stimulation between migraine patients and control group at interstimulus interval(ISI) of 0.3 sec. However, there was no difference between patients of MOA and MWA at each ISI. Conclusion: Although this study shows the possibility that at least the head pain mechanism in both MOA and MWA shares a common mechanism, more refined future study for larger number of cases is needed to confirm. Korean Journal of Headache 3(2):105-109, 2002
한국인 편두통 환자와 미토콘드리아 DNA 11,084 유전자 다형성의 연관성
Byung-Kun Kim, Hee-Joon Bae, Ja-Seong Koo, Oh-Hyun Kwon, Man-Ho Kim
Korean J Headache. 2002;3(2):111-115.   Published online December 31, 2002
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AbstractAbstract PDF
Background
The genetic and molecular basis of migraine is still unknown. Clinical similarities bet- ween migraine and mitochondrial encephalomyopathies and the bias toward maternal transmission in family studies suggest that mitochondrial DNA(mtDNA) may play a role in migraine pathogenesis. An A-11,084-G substitution at mtDNA, has been reported in 25% of Japanese migraineurs. In contrast, in Danish individuals, this A-to-G mutation at mtDNA 11,084 was detected neither in persons with mig- raine nor in persons who had never had migraine. The aim of the present study was to investigate the frequency of this mutation in Korean migraineurs. Methods: One hundred migraineurs were studied after obtaining informed consent. A diagnosis of migraine was made on the basis of the International Headache Society criteria. DNA was purified from whole blood using DNA purification kit. For the analysis of mitochondrial nucleotide A-11,084-G substi- tution, mtDNA(bases 10,835 to 11,236) was amplified by polymerase chain reaction(PCR) using primers described previously. An A-11,084-G substitution generates BsmI restriction site. BsmI site containing PCR product(13,031~13,610 bases) was also amplified for positive-control. The amplified products were digested with 1 unit of BsmI, and were sized on a 1% TAE agarose gel with 100-bp DNA ladder marker. Results: None of the PCR products were cleaved by BsmI, whereas the positive controls were all digested by BsmI. We failed to detect the mtDNA A-11084-G substitution in our Korean patients with migraine. Conclusions: Mitochondrial DNA A to G polymorphism at 11,084 is not a risk factor for Korean mig- raineurs. This mutation may be rare in non-Japanese populations, which suggests ethnic difference in SNP genotype. Korean Journal of Headache 3(2):111-115, 2002
두개내 고압과 두개내 저압을 교대로 보인 두통 환자 1예
Sun J. Chung, Sun U. Kwon, Jong S. Kim
Korean J Headache. 2002;3(2):117-118.   Published online December 31, 2002
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AbstractAbstract PDF
Headache caused by intracranial hypertension is quite different from that caused by intracranial hypotension. We report a patient presenting with alternating intracranial hypertension and intracranial hypotension during the treatment of severe headache. The severe headache and decreased visual acuity resolved with the revision of the cistoperitoneal shunt. Korean Journal of Headache 3(2):117-118, 2002
BOOK REVIEW - 통증학 Ⅰ, Ⅱ
Korean J Headache. 2002;3(2):121-122.   Published online December 31, 2002
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IMAGES OF HEADACHE - 측두 동맥염의 양상으로 발현된 비인두암
Korean J Headache. 2002;3(2):123-124.   Published online December 31, 2002
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Headache and Pain Research : Headache and Pain Research