Abstract

Background
and Objectives: Restless leg syndrome(RLS) is a prevalent disease which is often mis- diagnosed or underdiagnosed. RLS and migraine share some clinical features such as depression, sleep disorders, hemodialysis and positive family history of the disease. We analyzed the data of Hallym uni- versity migraine in nurses study to identify the association of RLS and migraine. Method: All 1501 nurses working at Hallym Medical Center were asked 72-item questionnaire on migraine including general information, occupational environments and characteristics, characteristics of headache, triggering factors, management of headache and migraine related disabilities. The diagnosis of RLS was made according to 3-item question set which was incorporated in the above questionnaire. The completed questionnaires were analyzed for the association of RLS and migraine. Results: 1341(89.3%) participants completed the questionnaire. All were female with mean age of 27.5±5.7. Based on ICHD-II, 276(17.5%) had migraine. Among migraineurs, 57(20.6%) have aura. 23(1.7%) had RLS and 9(39.1%) of them had migraine. The prevalence of RLS was significantly higher among migraineurs(3.4%) than non-migraineurs(1.3%). Migraineurs with RLS had tendency to have more aura than migraineurs without RLS. There was no significant difference in attack frequency, headache severity and MIDAS scores between migraineurs with RLS and migraineurs without RLS. Conclusion: There was significantly higher prevalence of RLS among migraineurs. Migraine with RLS showed tendency to have more aura.