Klebsiella pneumoniae usually causes pneumonia, pyogenic liver abscess, and bacteremia. Meningitis is a rare form of Klebsiella infection. We report a case of Klebsiella meningitis associated with liver abscess, renal abscess, and endoph- thalmitis. A 69-year-old man presented with headache, fever and altered mentality. Antibiotic therapy was administered under the impression of bacterial meningitis based on brain CT and CSF examination. Despite the improvement of CSF profiles, patient was deteriorated with aggravation of laboratory profile such as liver enzyme, bilirubin, and creatinine levels. Multiple liver and renal abscesses were found on abdominal CT and treated with abscess drainage. Klebsiella was isolated in blood, urine and liver abscess cultures. During the hospitalization, endophthalmitis occurred and resulted in visual loss despite treatment. Klebsiella infection should be considered as one of causative pathogen in case of meningitis associated with abscess and endophthalmitis.