Abstract

Acyclovir is an effective agent for the treatment of herpes simplex and herpes zoster infections. Encephalopathy induced by acyclovir is an infrequent but well recognized adverse effect of acyclovir. But reversible posterior leukoen- cephalopathy(RPLE) induced by acyclovir is much less frequent, and there has been no report in Korea. We report a patient who developed RPLE after parenteral acyclovir administration.