Abstract

Histiocytic necrotizing lymphadenitis is a benign disease of the lymph node and spontaneously recovered within 4 to 6 months. Involvement of central nervous system rarely occurs as a form of aseptic meningitis. A 20 year-old woman presented with fever and headache. CSF studies revealed pleocytosis and elevated protein levels. Her symptoms were improved without specific management, but after several days generalized edema, multiple arthralgia and painful lymph node swelling with leukopenia were developed. A cervical lymph node biopsy disclosed necrotizing lymphadenitis. We report a patient with necrotizing lymphadenitis followed by aseptic meningitis.