- Migraines in Women: A Focus on Reproductive Events and Hormonal Milestones
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Seonghoon Kim, Jeong Wook Park
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Headache Pain Res. 2024;25(1):3-15. Published online April 5, 2024
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DOI: https://doi.org/10.62087/hpr.2024.0003
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- Migraine, a prevalent neurological disorder, is more common in women than in men. This sex difference is more pronounced after menarche and diminishes after menopause. Migraines in women are influenced by the menstrual cycle, pregnancy, and lactation, suggesting a connection to sex hormones, known as the estrogen withdrawal theory. Beyond endogenous hormonal changes accompanying reproductive events, exogenous hormonal factors such as contraceptives or hormone replacement therapy may also affect migraines. The hormonal influence cannot be explained simply by serum estrogen levels; instead, it involves a complex interplay of various factors. Here, we delineate aspects of migraines associated with endogenous and exogenous hormonal changes over the course of a woman’s life, exploring the mechanisms and contributing factors through which sex hormones influence migraines.
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Citations
Citations to this article as recorded by 
- Framing and Management of Migraines in Women: An Expert Opinion on Challenges, Current Approaches, and Future Multidisciplinary Perspectives
Piero Barbanti, Rossella E. Nappi Healthcare.2025; 13(2): 164. CrossRef - Morning Headaches: An In-depth Review of Causes, Associated Disorders, and Management Strategies
Yooha Hong, Mi-Kyoung Kang, Min Seung Kim, Heejung Mo, Rebecca C. Cox, Hee-Jin Im Headache and Pain Research.2025; 26(1): 66. CrossRef - Calcitonin Gene-Related Peptide Monoclonal Antibody Treatment in Nine Cases of Persistent Headache Following COVID-19-Infection
Soyoun Choi, Yooha Hong, Mi-Kyoung Kang, Tae-Jin Song, Soo-Jin Cho Journal of Korean Medical Science.2025;[Epub] CrossRef - Migraine in Women: Inescapable Femaleness?
Soo-Kyoung Kim Headache and Pain Research.2024; 25(1): 1. CrossRef - Three-month treatment outcome of medication-overuse headache according to classes of overused medications, use of acute medications, and preventive treatments
Sun-Young Oh, Jin-Ju Kang, Hong-Kyun Park, Soo-Jin Cho, Yooha Hong, Mi-Kyoung Kang, Heui-Soo Moon, Mi Ji Lee, Tae-Jin Song, Young Ju Suh, Min Kyung Chu Scientific Reports.2024;[Epub] CrossRef - Subjective Cognitive Decline Patterns in Patients with Migraine, with or without Depression, versus Non-depressed Older Adults
Sun Hwa Lee, Soo-Jin Cho Headache and Pain Research.2024; 25(2): 103. CrossRef - Understanding the Connection between the Glymphatic System and Migraine: A Systematic Review
Myoung-Jin Cha, Kyung Wook Kang, Jung-won Shin, Hosung Kim, Jiyoung Kim Headache and Pain Research.2024; 25(2): 86. CrossRef
- Diagnosis of Cervicogenic Headache
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Dae Woong Bae, Ko-Eun Choi, Seonghoon Kim, Jeong Wook Park
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Published online June 30, 2021
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- 경부인성 두통의 진단
- Sleep Deprivation and Headache
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Seonghoon Kim, Dae-Woong Bae, Ju Hee Oh, Jeong Wook Park
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Published online December 31, 2020
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- 수면 박탈과 두통
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