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Review Article
- The Current Role of Artificial Intelligence in the Field of Headache Disorders, with a Focus on Migraine: A Systemic Review
- Wonwoo Lee, Min Kyung Chu
- Headache Pain Res. 2025;26(1):48-65. Published online February 17, 2025
- DOI: https://doi.org/10.62087/hpr.2024.0024
- 269 View
- 22 Download
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Abstract
PDF - The application of artificial intelligence (AI) in the field of headache disorders, particularly migraine, is rapidly expanding, and AI has demonstrated significant potential for diagnosis, treatment, and research. This review examines the current role of AI in migraine management, categorizing AI applications into diagnosis and classification, assessment of treatment response, prediction of migraine attacks, and research. A systematic search of literature published between 2000 and 2024 was conducted, following PRISMA guidelines and utilizing the snowball technique. Of the 398 articles identified, along with five additional articles, 61 were finally reviewed. The results highlight promising AI applications, including the use of patient questionnaires, natural language processing, and imaging for migraine diagnosis, as well as predicting treatment responses and forecasting migraine attacks. Nonetheless, challenges remain in improving the accuracy, generalizability, validation, and clinical relevance of AI applications. Despite the substantial promise of AI for improving migraine management, it does not always guarantee better results than traditional methods. Careful consideration of the study design and method selection is crucial. Additionally, the interpretation of AI-generated results, particularly those from generative models, requires caution to avoid potential pitfalls.
Original Article
- Cluster Headache Characteristics and the Severity of Obstructive Sleep Apnea: Insights from Polysomnography Analysis
- Yooha Hong, Mi-Kyoung Kang, Min Kyung Chu, Soo-Jin Cho, Hee-Jin Im
- Headache Pain Res. 2024;25(1):63-71. Published online April 16, 2024
- DOI: https://doi.org/10.62087/hpr.2024.0001
- 1,230 View
- 30 Download
- 1 Citations
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Abstract
PDF
- Purpose: Cluster headache (CH) is characterized by circadian rhythmicity of the attacks, and it is known to respond exceptionally well to oxygen therapy. Furthermore, obstructive sleep apnea (OSA) frequently co-occurs with CH, and both conditions may be parallel outcomes of hypothalamic dysfunction rather than being causally related. The aim of this study was to analyze the association between CH characteristics and polysomnographic factors stratified by the severity of OSA in patients diagnosed with CH and OSA.
Methods
We retrospectively analyzed the data of OSA patients with CH who were enrolled in the Korean Cluster Headache Registry and underwent polysomnography due to clinical suspicion of OSA. Basic demographic data, headache-related parameters, and polysomnographic parameters were analyzed according to the severity of OSA (apnea-hypopnea index: <15 or ≥15 per hour).
Results
Twelve CH patients with OSA were evaluated. The onset age of CH was higher (38.5 years vs. 19.0 years, p=0.010), and the maximal duration of cluster bouts was longer (156.5 days vs. 47.0 days, p=0.037) in the moderate-to-severe OSA group than in the mild OSA group. Unlike other polysomnographic parameters, the apnea-hypopnea index and respiratory arousal index during rapid eye movement (REM) sleep were comparable across different OSA severity levels.
Conclusion
The onset age and duration of cluster bouts were associated with the severity of OSA in CH patients. Additionally, the relatively high susceptibility to hypoxia during REM sleep in patients with mild OSA implies that interventions may be potentially advantageous, even in CH patients with mild OSA. -
Citations
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- Morning Headaches: An In-depth Review of Causes, Associated Disorders, and Management Strategies
Yooha Hong, Mi-Kyoung Kang, Min Seung Kim, Heejung Mo, Rebecca C. Cox, Hee-Jin Im
Headache and Pain Research.2025; 26(1): 66. CrossRef
- Morning Headaches: An In-depth Review of Causes, Associated Disorders, and Management Strategies
Reiview Article
- Sleep Disorders in Headache Patients
- Hye Jeong Lee, Hee-Jin Im, Soo-Jin Cho, Min Kyung Chu
- Korean J Headache. 2023;24(1):1-10. Published online June 30, 2023
- 462 View
- 35 Download
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Abstract
PDF
- Headache disorders and sleep problems are common conditions with a high prevalence in the general population, and impose a considerable socio-economic burden. They show a close association with headache disorders through various relationship. The prevalence of sleep problems is elevated in individuals with headache, especially for migraine. In most headache disorders, sleep problems are accompanied by the deterioration of clinical characteristics of headache disorders. The sharing brain structures and neurotransmitters involved in the pathogenesis of headache disorders and sleep disorders may be an explanation for the close relationship between two disorders. In this article, we briefly review the relationship of headache disorders with sleep disorders including insomnia, sleep-related breathing disorders, central disorders of hypersomnolence, circadian rhythm sleep-wake disorders, parasomnias, and sleep related movement disorders.
- Comorbid Medical Conditions in Patients with Medication Overuse Headache: Multicenter Prospective Medication Overuse Headache Registry Analysis
- Yooha Hong, Soo-Jin Cho, Min Kyung Chu, Sun-Young Oh, Heui-Soo Moon, Tae-Jin Song, Mi Ji Lee, Jin-Ju Kang, Hong-Kyun Park
- Published online December 31, 2021
- 321 View
- 56 Download
- Diagnostic Delay of Cluster Headache in Korea
- Byung-Su Kim, Soo-Kyoung Kim, Pil-Wook Chung, Byung-Kun Kim, Mi Ji Lee, Min Kyung Chu, Jin-Young Ahn, Dae Woong Bae, Tae-Jin Song
- Published online June 30, 2020
- 492 View
- 154 Download
- Cluster-like Headache in a Patient with Border-zone Infarction and Internal Carotid Artery Stenosis
- Ki-Moon Jang, Hye-jeong Lee, Seo-yeon Gwak, Min Kyung Chu
- Published online December 31, 2019
- 309 View
- 45 Download
- Does Caffeine Trigger Migraine Attack? A Smartphone Headache Diary Study
- Hyun Suk Kim, Kee Hwan Pae, Dong Jin Shin, Hyeon Mi Park, Seok Hong Choi, Hyun Joon Lee, Du Hwan Kim, Jae Hoon Chung, Sung Jong Eun, Min Kyung Chu, Dong Hoon Shin
- Published online December 31, 2019
- 449 View
- 116 Download
- A Case of Spontaneous Intracranial Hypotension Presenting Normal Cerebrospinal Fluid Pressure
- Bo Kyu Choi, Jae Wook Jung, Han Kyu Na, Tae Won Kim, Min Kyung Chu
- Published online December 31, 2019
- 375 View
- 41 Download
- A Case of Superior Orbital Fissure Syndrome Attributed to Sinusitis Presenting Unilateral Throbbing Headache
- Byung-Su Kim, Byung-Kun Kim, Soo-Kyoung Kim, Jae-Moon Kim, Heui-Soo Moon, Kwang-Yeol Park, Jong-Hee Sohn, Tae-Jin Song, Min Kyung Chu, Myoung-Jin Cha, Soo-Jin Cho, J
- Published online December 31, 2017
- 480 View
- 111 Download
- The Frequency and Characteristics of Other Primary Headache Disorders in First-Visit Headache Patients in Korea: A Multicenter Study
- Myoung-Jin Cha, Byung-Kun Kim, Byung-Su Kim, Jong-Hee Sohn, Soo-Kyoung Kim, Heui-Soo Moon, Tae-Jin Song, Jae-Moon Kim, Jeong Wook Park, Min Kyung Chu, Kwang-Yeol Park
- Published online December 31, 2017
- 486 View
- 89 Download
- A Case of Short-lasting Unilateral Neuralgiform Headache Attacks with Conjunctival Injection and Tearing (SUNCT) which Showed a Favorable Response with Rregabalin
- Bohm Choi, Myung Jin Son, Donggook Kang, Min Kyung Chu
- Published online June 30, 2016
- 758 View
- 107 Download
- Clinical Factors Influencing Headache Impact Test-6 in Migraine and Tension-type Headache Patients
- Jong Hee Sohn, Min Kyung Chu, Soo-Jin Cho
- Published online December 31, 2015
- 561 View
- 90 Download
- Aggravation by Routine Physical Activity and Associated Factors in the Korean Migraine Population
- Byung-Su Kim, Min Kyung Chu, Byung-Kun Kim, Jae-Moon Kim
- Published online June 30, 2015
- 976 View
- 181 Download
- The Prevalence and Associated Clinical Factors of Dizziness in Migraine and Tension-type Headache - Preliminary Study
- Jong Hee Sohn, Min Kyung Chu, Soo-Jin Cho
- Published online December 31, 2014
- 442 View
- 87 Download
- Physical Activity in Migraine and Tension-type Headache
- Si-Won Eum, Min Kyung Chu, Jong Hee Sohn, Min-Woo Koo, Soo-Jin Cho
- Published online June 30, 2014
- 831 View
- 197 Download
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