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HOME > Headache Pain Res > Volume 25(2); 2024 > Article
Editorial
 When Should Headache Specialists Hold a Needle? The Role of Botulinum Toxin Injections and Occipital Nerve Blocks
Soo-Jin Choorcid
Headache and Pain Research 2024;25(2):73-74.
DOI: https://doi.org/10.62087/hpr.2024.0020
Published online: October 17, 2024

Department of Neurology, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Republic of Korea

Correspondence: Soo-Jin Cho, M.D., Ph.D. Department of Neurology, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, 7 Keunjaebong-gil, Hwaseong 18450, Republic of Korea Tel +82-31-8086-2310, Fax +82-31-8086-2317, E-mail: dowonc@naver.com
• Received: June 28, 2024   • Revised: September 16, 2024   • Accepted: October 1, 2024

© 2024 The Korean Headache Society

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The management of patients with primary headaches, particularly migraines, involves taking a detailed history, accurately diagnosing the condition, evaluating the patient, confirming the diagnosis with tests, and selecting appropriate acute and prophylactic medications. Injectable treatments are typically reserved for patients who have not responded to pharmacological treatments or for those for whom injectable therapies have proven more effective. Therefore, when should injection therapy be recommended?
The absolute indication for botulinum toxin injections is chronic migraine. This issue features the article “What a neurologist should know about functional anatomy for botulinum toxin injections in the head, face, and neck: a practical perspective,” which thoroughly explains the complexity of the muscles and associated target nerves in the frontal, temporal, and occipital areas, as well as the basic functional anatomy.1 The diagnostic criteria for chronic migraine include experiencing headaches for at least 3 months, with 15 or more headache days per month, and at least 8 of those days meeting the criteria for migraine. Additionally, botulinum toxin injections may be considered for patients with trigeminal neuralgia, short-lasting unilateral neuralgiform headache attacks, and high-frequency episodic migraine, but only after a thorough explanation and consent, and if other pharmacological therapies prove ineffective or cause severe adverse effects.2
The absolute indications for occipital nerve blocks with local anesthetics are cluster headaches (sometimes with a steroid) and occipital neuralgia. Nerve blocks can also be performed with local anesthetics on the trigeminal nerve or its branches, such as the supraorbital and auriculotemporal nerves, to manage trigeminal neuralgia, herpes zoster, migraine, or various headache and cranial pain disorders.3 Compared to botulinum toxin injections, nerve blocks are less expensive, require fewer injections, and can be administered more frequently—weekly or monthly, depending on the patient’s needs. The article “Bilateral greater occipital nerve block for preventing the onabotulinumtoxinA wear-off phenomenon in the treatment of chronic migraine: a case series of 12 patients” discusses the use of an additional greater occipital nerve block in the 2nd month following botulinum toxin injections to mitigate the wear-off phenomenon.4,5 Therefore, nerve blocks and botulinum toxin injections can be administered either on the same day or on separate days.5
What are some strategies to alleviate the pain of injections or to encourage patient acceptance of them? Patients who experience anxiety, allodynia, or who are at a high risk of seizures or fainting may be reluctant to undergo injectable treatments. Nonetheless, injectable treatments can improve the overall effectiveness of the therapy and provide a quiet moment to converse with the patient.
Simple warnings before the injection, such as “It’s going to sting,” and conversation during the injection are common techniques professionals use to alleviate the discomfort associated with injections. They also emphasize careful monitoring for hemostasis and ensuring the patient is relaxed to minimize the risk of bleeding or bruising. Once patients experience the benefits of nerve block therapy, they may be more open to considering botulinum toxin or other injectable treatments. A headache specialist might frequently use a needle in their practice, especially for patients without contraindications.
  • 1. Kim SR, Favero V, Kim AH, Kim ST. What a neurologist should know about functional anatomy for botulinum toxin injections in the head, face, and neck: a practical perspective. Headache Pain Res 2024;25:77-85.Article
  • 2. Dach F, Éckeli ÁL, Ferreira Kdos S, Speciali JG. Nerve block for the treatment of headaches and cranial neuralgias - a practical approach. Headache 2015;55 Suppl 1:59-71.ArticlePubMed
  • 3. Kang MK, Cho SJ. SUNCT, SUNA and short-lasting unilateral neuralgiform headache attacks: debates and an update. Cephalalgia 2024;44:3331024241232256.ArticlePubMedPDF
  • 4. Karaoğlan M. Three men in a boat: the comparison of the combination therapy of botulinum toxin and greater occipital nerve block with bupivacaine, with botulinum toxin monotherapy in the management of chronic migraine. Clin Neurol Neurosurg 2023;226:107609.ArticlePubMed
  • 5. Kim S, An JY, Bae DW. Bilateral greater occipital nerve block for preventing the onabotulinumtoxinA wear-off phenomenon in the treatment of chronic migraine: a case series of 12 patients. Headache Pain Res 2024;25:111-116.Article

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      When Should Headache Specialists Hold a Needle? The Role of Botulinum Toxin Injections and Occipital Nerve Blocks
      Headache Pain Res. 2024;25(2):73-74.   Published online October 17, 2024
      DOI: https://doi.org/10.62087/hpr.2024.0020
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